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N-(p-Aminobenzoyl)glutamic acid

Product Name
N-(p-Aminobenzoyl)glutamic acid
CAS No.
4271-30-1
Chemical Name
N-(p-Aminobenzoyl)glutamic acid
Synonyms
N-(4-AMINOBENZOYL)-L-GLUTAMIC ACID;Methotrexate EP Impurity K;(2S)-2-(4-Aminobenzamido)pentanedioic Acid;(2S)-2-[(4-Aminobenzoyl)amino]pentanedioic Acid;NSC 71042;H-4-ABZ-GLU-OH;Folic acid iMpurity A;Methotrexate Impurity K;Folic Acid EP Impurity A;Folic acid impurity A CRS
CBNumber
CB2193546
Molecular Formula
C12H14N2O5
Formula Weight
266.25
MOL File
4271-30-1.mol
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N-(p-Aminobenzoyl)glutamic acid Property

Melting point:
~175 °C (dec.)
alpha 
-15 º (c=2% in 0.1N HCl)
Boiling point:
409.45°C (rough estimate)
Density 
1.2846 (rough estimate)
refractive index 
1.6660 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Aqueous Base (Sparingly), Aqueous Acid (Sparingly), DMSO (Sparingly)
pka
3.50±0.10(Predicted)
color 
White to Light
Merck 
14,426
BRN 
2816320
Stability:
Hygroscopic
InChIKey
GADGMZDHLQLZRI-VIFPVBQESA-N
CAS DataBase Reference
4271-30-1(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
HS Code 
2924296000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A0879
Product name
N-(4-Aminobenzoyl)-L-glutamic acid
Purity
≥98% (TLC)
Packaging
5g
Price
$470
Updated
2024/03/01
Sigma-Aldrich
Product number
1019870
Product name
N-(4-Aminobenzoyl)-L-glutamic acid
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$436
Updated
2024/03/01
TCI Chemical
Product number
A0442
Product name
N-(4-Aminobenzoyl)-L-glutamic Acid
Purity
>97.0%(T)
Packaging
1g
Price
$97
Updated
2024/03/01
TCI Chemical
Product number
A0442
Product name
N-(4-Aminobenzoyl)-L-glutamic Acid
Purity
>97.0%(T)
Packaging
5g
Price
$315
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0001242
Product name
Folic acid impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001242
Price
$220
Updated
2024/03/01
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N-(p-Aminobenzoyl)glutamic acid Chemical Properties,Usage,Production

Chemical Properties

Light Tan Waxy Solid

Uses

Major metabolite of 5-Methyltetrahydrofolic Acid

Uses

Marker in folate metabolism studies.

Definition

ChEBI: A dipeptide resulting from the formal condensation of the carboxylic acid group of 4-aminobenzoic acid with the amino group of L-glutamic acid.

Purification Methods

Crystallise the acid from H2O. Also purify it by dissolving 2.7g in H2O (130mL), adding aqueous NaOH to pH 5.5 and adding portionwise a solution of 0.5M CuSO4 to complete precipitation of the Cu salt. This salt is filtered off, suspended in H2O and H2S is bubbled through to precipitate CuS, filter, evaporate and recrystallise the residue from H2O. It has max (H2O) at 273nm. [Backer & Houtman Recl Trav Chim Pays-Bas 70 738, 743 1951, Beilstein 14 IV 1153.]

N-(p-Aminobenzoyl)glutamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(p-Aminobenzoyl)glutamic acid Suppliers

BOC Sciences
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1-631-485-4226; 16314854226
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United States
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+1-650-486-1361
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sales@hbcchem.com
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16314854226
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86-714-3992388
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overseasales1@yongstandards.com
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United States
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Cato Research Chemicals Inc.
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020-81215950 4000-868-328
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United States
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Aladdin Scientific
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View Lastest Price from N-(p-Aminobenzoyl)glutamic acid manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
N-(4-Aminobenzoyl)-L-glutamic acid 4271-30-1
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-03-25
airuikechemical co., ltd.
Product
N-(4-aminobenzoyl)-L-glutamic acid 4271-30-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-07
PNP Biotech Co. Ltd
Product
N-(4-Aminobenzoyl)-L-glutamic acid 4271-30-1
Price
US $0.00/kg
Min. Order
25kg
Purity
HPLC>99%
Supply Ability
Inquiry
Release date
2022-09-16

4271-30-1, N-(p-Aminobenzoyl)glutamic acidRelated Search:


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  • NSC 71042
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  • Folic Acid Impurity 1(Folic Acid EP Impurity A)
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  • Methotrexate EP Impurity K (Folic Acid EP Impurity A)
  • N-(4-Aminobenzoyl)-L-glutamic acid, ≥98% (TLC)
  • Folic acid Impurity AQ: What is Folic acid Impurity A Q: What is the CAS Number of Folic acid Impurity A Q: What is the storage condition of Folic acid Impurity A
  • 4-Aminobenzoylglutamic Acid (F0M031)
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